Synthesis and configuration of 4-alkyl-2-methyl-3,4-diphenyl-1,2-thiazetidine 1,1-dioxide |
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| Authors: | Evelyne Grander Grard Leclerc Jean-Daniel Ehrhardt |
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| Institution: | Evelyne Grander,Gérard Leclerc,Jean-Daniel Ehrhardt |
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| Abstract: | 4-Alkyl-2-methyl-3,4-diphenyl-1,2-thiazetidine 1,1-dioxide 5, 6 and 7 were obtained from 2-methyl-3,4-diphenyl-1,2-thiazetidine 1,1-dioxide 1 by reaction of its anion 4 with alkyl halides. cis- and trans-Configuration of the 4-alkylated products were determined by 1H-nmr and NOE difference spectro-scopy studies. |
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