The synthesis and properties of 2-substituted dihydropyrimidines

Various 2-substituted 1,4-dihydro-4,4,6-trimethyl-1-phenylpyrimidines and 1,6-dihydro-4,6,6-trimethylpyrimidines were synthesized independently. For these dihydropyrimidines, the physical data such as the uv, ir, and nmr spectra and the oxidation potential were compared. 2-Dimethylamino substituted dihydropyrimidine showed the lowest oxidation potential, which expected the similar reducing ability as dihydropyridines.