Design,Synthesis and in vitro Evaluation of a New Class of Novel Cyclooxygenase-2 Inhibitors:3,4-diaryl-3-pyrrolin-2-ones |
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| Authors: | Ai Ping BAI Zong Ru GUO Wen Hui HU Fang SHEN Gui Fang CHENG Institute of Materia Medica Chinese Academy of Medical Science Peking Union Medical College Beijing |
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| Affiliation: | Ai Ping BAI,Zong Ru GUO*,Wen Hui HU,Fang SHEN,Gui Fang CHENG Institute of Materia Medica,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100050 |
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| Abstract: | design, synthesis and in vivo evaluation of a new class of COX-2 inhibitors 3, 4-diaryl-3-pyrrolin-2-ones are reported. |
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| Keywords: | Cyclooxyenase-2 inhibitor NSAIDs (non-steroidal anti-inflammatory drugs). |
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