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Synthesis and Properties of a Novel FRET-Based Ratiometric Fluorescent Sensor for Cu2+
Authors:Shao Li  Di Zhang  Min Wang  Saige Ma  Jihong Liu  Yufen Zhao  Yong Ye
Affiliation:1.Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering,Zhengzhou University,Zhengzhou,China;2.Institute of Agricultural Quality Standards and Testing Technology, Henan Academy of Agricultural Sciences,Zhengzhou,China;3.Department of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education),Tsinghua University,Beijing,China
Abstract:A novel FRET-based probe LS3 was designed and synthesized. As expected, it exhibited high selectivity and sensitivity for detecting Cu2+ over other commonly coexistent metal ions. The detection limit was measured to be 0.0423 μM for Cu2+, which can meet the selective requirements for practical application. In addition, the newly synthesized compound 3a/b have potential value of further synthesizing more analogous FRET-based probes.
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