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Visible-Light-Mediated Controlled Radical Branching Polymerization in Water |
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| Authors: | Kriti Kapil Dr Grzegorz Szczepaniak Dr Michael R Martinez Dr Hironobu Murata Dr Arman Moini Jazani Jaepil Jeong Prof Dr Subha R Das Prof Dr Krzysztof Matyjaszewski |
| Institution: | 1. Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213 USA;2. Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213 USA
Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland;3. Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213 USA Center for Nucleic Acids Science & Technology, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213 USA |
| Abstract: | Hyperbranched polymethacrylates were synthesized by green-light-induced atom transfer radical polymerization (ATRP) under biologically relevant conditions in the open air. Sodium 2-bromoacrylate (SBA) was prepared in situ from commercially available 2-bromoacrylic acid and used as a water-soluble inibramer to induce branching during the copolymerization of methacrylate monomers. As a result, well-defined branched polymethacrylates were obtained in less than 30 min with predetermined molecular weights (36 000<Mn<170 000), tunable degree of branching, and low dispersity values (1.14≤Đ≤1.33). Moreover, the use of SBA inibramer enabled the synthesis of bioconjugates with a well-controlled branched architecture. |
| Keywords: | ATRP Bioconjugate Hyperbranched Inibramer Polymethacrylate |