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Antiparasitic agents produced by microorganisms
Authors:Kazuro Shiomi,Satoshi Ō  mura
Affiliation:*)School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan; **)Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University and The Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
Abstract:Microorganisms produce many useful antiparasitic agents. Antiparasitic activities and biochemical targets of antiprotozoal and anthelmintic antibiotics are reviewed. Antimalarial apicidin, thiolactomycin, fosmidomycin, and borrelidin, antitrypanosomal ascofuranone, and nematocidal emodepside, 2-deoxoparaherquamide A, and nafuredin are recently discovered antibiotics, and they have potential as useful drugs.
Keywords:Antibiotics   antiparasite   antiprotozoal   anthelmintic
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