| New Polypeptides from Chinese Mistletoe, Viscum coloratum （Kom.） Nakai |
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| 引用本文： | Shi Lei LIU Xiu Bao DU Jing Lin KONG. New Polypeptides from Chinese Mistletoe, Viscum coloratum （Kom.） Nakai[J]. 中国化学快报, 2006, 17(1): 41-44 |
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| 作者姓名： | Shi Lei LIU Xiu Bao DU Jing Lin KONG |
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| 作者单位： | Shi Lei LIU，Xiu Bao DU，Jing Lin KONG Research Institute of Chemical Defense，Beijing 102205 |
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| 摘 要： | Mistletoes are perennial evergreen, semi-parasitic plants growing on branches or stems of deciduous trees. As a medical plant, mistletoe has the reputation of “magic herb” in Europe and has been used for numerous conditions. Its aqueous extractions have…
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| 关 键 词： | 多肽 中国槲寄生 分离 一级结构 粘毒素 中药 抗癌活性 |
| 收稿时间： | 2005-05-08 |
New Polypeptides from Chinese Mistletoe,Viscum coloratum (Kom.) Nakai |
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| Shi Lei LIU,Xiu Bao DU,Jing Lin KONG. New Polypeptides from Chinese Mistletoe,Viscum coloratum (Kom.) Nakai[J]. Chinese Chemical Letters, 2006, 17(1): 41-44 |
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| Authors: | Shi Lei LIU Xiu Bao DU Jing Lin KONG |
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| Abstract: | Three viscotoxins have been isolated from Chinese mistletoe, Viscum coloratum (Kom.) Nakai. The primary structures were determined unambiguously by the combination of Edman degradation, endoproteinase Elu-c digestion, and Q-TOF mass spectrometry. One was identified as viscotoxin C1, which was for the first time isolated from Chinese mistletoe. The other two were new polypeptides, named as viscotoxin B5 and viscotoxin B8. Pharmacological studies showed that the polypeptides exhibit distinct cytotoxicity to human cancer cells. |
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| Keywords: | Viscum coloratum mistletoe isolation primary structure viscotoxin. |
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