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Mass spectrometric amino acid sequence determination in arginine-containing peptides |
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| Authors: | M. M. Shemyakin E. I. Vinogradova Yu. A. Ovchinnikov A. A. Kiryushkin M. Yu. Feigina N. A. Aldanova Yu. B. Alakhov V. M. Lipkin B. V. Rosinov L. A. Fonina |
| Affiliation: | Institute for Chemistry of Natural Products, USSR Academy of Sciences, Moscow, USSR |
| Abstract: | Methods of converting arginine residues into ornithine, Nδ-pyrimidylornithine, Nδ-imidazolidinonidenornithine residues in peptides have been developed. The modified peptides undergo the amino acid type of fragmentation, so that mass spectrometry can now be used for amino acid sequence determination in arginine-containing peptides. |
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