The absorption of iodine-131 on a ceramic matrix |
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Authors: | H. S. Han U. J. Park A. Dash |
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Affiliation: | (1) Korea Atomic Energy Research Institute, P.O. Box 105, 305-600 Yusung, Daejeon, Korea;(2) Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai-400085 Trombay, India |
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Abstract: | The retention of 131I on ceramic rod coated with silver nitrate followed by coating with a polyurethane membrane to be applied in brachytherapy was studied. The concentration of silver nitrate (20 g/l), the volume of 131I as a sodium iodide solution (100 µl), the pH of the reaction mixture (pH 9) etc., were optimized to get a maximum uptake on the ceramic rod. The concentration of coating solution (5%, polyurethane in tetrahydrofuran) was also optimized to obtain a minimum leaching of 131I activity in normal saline solution. After coating with a polyurethane membrane, the 131I absorbed on the ceramic rod exhibited low leachability (0.03%). This method can be applied for the preparation of 125I interstitial sources to be used in eye and prostate cancer therapy. |
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