Redox Divergent Synthesis of Fawcettimine‐Type Lycopodium Alkaloids |
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| Authors: | Dr Hisaaki Zaimoku Dr Tsuyoshi Taniguchi |
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| Institution: | School of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma‐machi, Kanazawa, 920‐1192 (Japan) |
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| Abstract: | A new approach for synthesis of fawcettimine‐type Lycopodium alkaloids is described. A divergent strategy was achieved by applying stereoselective Diels–Alder reaction followed by redox‐controlled elaboration. Eventually, (?)‐8‐deoxyserratinine, (+)‐fawcettimine, (?)‐lycopoclavamine‐A, (?)‐serratine, (?)‐lycopoclavamine‐B and (?)‐serratanidine were successfully accessed. |
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| Keywords: | asymmetric synthesis cycloaddition divergent synthesis natural products total synthesis |
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