Taming the Carboxyl Group for Directed Carbometalation: Observations on the Use of Anions,Dianions and Ester Enolates |
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| Authors: | Dr Sandy Desrat Dr Philip J Gray Dr Matthew R Penny Prof?Dr William B Motherwell |
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| Institution: | Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ (United Kingdom), Tel: +(44)?2076797524 |
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| Abstract: | Carboxylate anions, dianions and ester enolates provide simultaneous protection and activation for directed carbometalation reactions. Advantage can be taken of the bis‐carbanionic character of the intermediate for further controlled C?C bond forming reactions. |
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| Keywords: | allene carbometalation copper enolate Grignard reagent |
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