Rhodium‐Catalyzed Intramolecular [3+2+2] Cycloadditions between Alkylidenecyclopropanes,Alkynes, and Alkenes |
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| Authors: | Marisel Araya Moisés Gulías Dr. Israel Fernández Dr. Gaurav Bhargava Prof. Luis Castedo Prof. José Luis Mascareñas Dr. Fernando López |
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| Affiliation: | 1. Departamento de Química Orgánica and Centro Singularde, Investigación en Química Biológica y Materiales Moleculares (CIQUS), Universidad de Santiago de Compostela, 15782, Santiago de Compostela (Spain);2. Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040‐Madrid (Spain);3. Instituto de Química Orgánica General‐CSIC, Juan de la Cierva 3, 28006, Madrid (Spain) |
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| Abstract: | A Rh‐catalyzed intramolecular [3+2+2] cycloaddition is reported. The cycloaddition affords synthetically relevant 5,7,5‐fused tricyclic systems of type 2 from readily available dienyne precursors. The transformation takes place with moderate or good yields, high diastereoselectivity, and total chemoselectivity. |
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| Keywords: | alkylidenecyclopropane carbocycles catalysis cycloadditions rhodium |
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