Synthesis of regioisomeric naphtho-furans via naphthyloxyalkanals |
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| Authors: | H. Kwiecień M. Witczak M. Kowalewska M. Augustyniak |
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| Affiliation: | 1.Department of Organic Synthesis and Drug Technology,West Pomeranian University of Technology,Szczecin,Poland |
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| Abstract: | A new route to the regioisomeric 2-alkylnaphtho[2,1-b]- and 2-alkylnaphtho[1,2-b]furans via acid-catalyzed cyclization of the corresponding 2-naphthyloxyalkanals under mild conditions over Amberlyst 15 resin has been described. The 2-naphthyloxyalkanals were obtained by palladium-catalyzed reduction of 2-naphthyloxyalkanoyl chlorides. |
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