Preparation of optically pure (3E,5E)-alkyl-2-hydroxy-6-arylhexa-3,5-dienoates by Candida parapsilosis ATCC 7330 mediated deracemisation of the racemates |
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| Authors: | Vaijayanthi Thangavel |
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| Institution: | a Department of Chemistry, Indian Institute of Technology Madras, Chennai 600 036, Tamil Nadu, India
b Laboratory of Bioorganic Chemistry, Department of Biotechnology and National Center for Catalysis Research, Indian Institute of Technology Madras, Chennai 600 036, Tamil Nadu, India |
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| Abstract: | Biocatalytic deracemisation of a range of racemic (3E,5E)-alkyl-2-hydroxy-6-arylhexa-3,5-dienoates using Candida parapsilosis ATCC 7330 resulted in pure (S)-enantiomers in yields of up to 80% and ee>99%. |
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| Keywords: | (3E 5E)-Alkyl-2-hydroxy-6-arylhexa-3 5-dienoates Synthesis Biocatalytic deracemisation Candida parapsilosis |
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