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Amphiphilic bipolar duplex α-cyclodextrin forming vesicles
Authors:Dengxiang Dong  Yanli Cui  Matthieu Sollogoub  Yongmin Zhang
Affiliation:a Ecole Normale Supérieure, Département de Chimie, UMR 8642 CNRS, 24 rue Lhomond, F-75005 Paris, France
b Université Pierre et Marie Curie-Paris 6, Institut de chimie moléculaire (FR 2769), F-75005 Paris, France
c Ecole Normale Supérieure, Département de Chimie, UMR 8640 CNRS, 24 rue Lhomond, F-75005 Paris, France
d ZJU-ENS Joint Laboratory of Medicinal Chemistry, Zhejiang University, Hangzhou 310058, China
Abstract:We synthesized a duplex cyclodextrin with two aliphatic links and functionalized with eight pentyl ethers orientated towards the centre of the duplex. We found that this molecule self-assembled in water to form stable vesicles with a diameter within the range 1-10 μm.
Keywords:Cyclodextrins   Vesicles   Amphiphile
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