Supramolecular architectures of succinates of 1‐hydroxypropan‐2‐aminium derivatives

Aminoalkanol and aroxyalkyl derivatives are known as potential anticonvulsants. Two new salts, namely bis{(R,S)‐N‐2‐(2,6‐dimethylphenoxy)ethyl]‐1‐hydroxypropan‐2‐aminium} succinate ( 1s ), C₁₃H₂₂NO₂⁺·0.5C₄H₄O₄^2?, and bis{(S)‐(+)‐N‐2‐(2,6‐dimethylphenoxy)ethyl]‐1‐hydroxypropan‐2‐aminium} succinate ( 2s ), C₁₃H₂₂NO₂⁺·0.5C₄H₄O₄^2?, have been prepared and characterized by single‐crystal X‐ray diffraction. The N atoms are protonated by proton transfer from succinic acid. Salt 1s crystallizes in the space group P2₁/n with one cation and half an anion in the asymmetric unit across an inversion centre, while ( 2s ) crystallizes in the space group P2₁ with four cations and two anions in the asymmetric unit. The hydroxy group of the cation of 1s is observed in two R/S disorder positions. The crystals of these two salts display similar supramolecular architectures (i.e. two‐dimensional networks), built mainly by intermolecular N⁺—H…O^δ? and O—H…O^δ? hydrogen bonds, where `δ?' represents a partial charge. The succinate anions are engaged in hydrogen bonds, not only with protonated N atoms, but also with hydroxy groups.