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Reaction kinetics of resveratrol with tert-butoxyl radicals
Authors:Iva Džeba  Tomasz Pedzinski  Branka Mihaljević
Institution:1. Ru?er Bo?kovi? Institute, Divison of Materials Chemistry, Radiation Chemistry and Dosimetry Laboratory, Bijeni?ka 54, 10000 Zagreb, Croatia;2. Faculty of Chemistry, Adam Mickiewicz University, 60-780 Poznan, Poland;1. Dept. of Internal Medicine, Laboratory of Clinical and Nutritional Biochemistry, University of Perugia, I-06123 Perugia, Italy;2. Dept. of Chemistry, University of Natural Resources and Life Sciences, A-1190 Vienna, Austria;3. Health & Environment Dept., Environmental Resources and Technologies, Austrian Institute of Technology GmbH, A-3430 Tulln, Austria;4. Dept. of Chemistry and Industrial Chemistry, University of Pisa, I-56126 Pisa, Italy;5. Research and Development, DSM Nutritional Products, CH-4002 Basel, Switzerland;6. Institute of Pharmacology and Toxicology, Dept. of Biomedical Sciences, University of Veterinary Medicine Vienna, A-1210 Vienna, Austria;1. Technical University of Crete, Department of Environmental Engineering, Polytechneioupolis, GR-73100 Chania, Greece;2. Institute of Electronic Structure and Laser (IESL), FORTH, P.O. Box 1527, Vasilika Vouton, GR-71110 Heraklion, Greece;1. Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland;2. National Medicines Institute, Chelmska 30/34, 00-725 Warsaw, Poland;3. Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland
Abstract:The rate constant for the reaction of t-butoxyl radicals with resveratrol was studied under pseudo-first order conditions. The rate constant was determined by measuring the phenoxyl radical formation rate at 390 nm as function of resveratrol concentration in acetonitrile. The rate constant was determined to be 6.5×108 M?1s?1. This high value indicates the high reactivity consistent with the strong antioxidant activity of resveratrol.
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