Sur le role fondamental du cation alcalin dans la reduction des cetones par les hydrures metalliques. Utilisation de coordinats macrocycliques—II: La stereoselection dans le cas ou intervient le modele cyclique (etude d'uen cetone aziridinique)

Dramatic changes in the stereoselectivity in the course of the reduction of N-tert-butyl 2-acetyl aziridine are observed when altering experimental procedures. Ratios 98% of the S^*R^* isomer and 75% of the R^*R^* isomer can be obtained. This phenomenon is controlled by the alkaline cation (Na⁺ or Li⁺). Utilization of macrocyclic ligands allows the reaction to be run free of the alkaline cation.