Synthese de C-nucleosides—IX : Purines substituees en position 8 par le desoxy-2 ribose |
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| Authors: | A Kolb C Gouyette T Huynh Dinh J Igolen |
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| Institution: | Laboratoire de Chimie Organique, Service de Chimie des Protéines, Institut Pasteur, 28, rue du Docteur Roux, 75015-Paris, France |
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| Abstract: | Benzyl 2-deoxy-3,5-di-O-p-toluyl-d-erythro-pentofuranosyl thioformimidate 3, prepared from nitrile 1, reacts with α-aminocyanoacetic acid derivatives to yield C-imidazole nucleosides which are further cyclized into purines. The 6-mercapto purine 2 is obtained in two different ways. |
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