DIHALOCARBENE ADDITION TO ARYLSUBSTTTUTED VINYL PHOSPHATES UNDER PHASE TRANSFER CATALYTIC CONDITIONS |
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| Authors: | Imre Petneházy György Keglevich László Tőke |
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| Institution: | Department of Organic Chemical Technology , Technical University Budapest , 1521, Budapest, Hungary |
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| Abstract: | Abstract Dihalocarbene addition to aryl-substituted vinyl phosphates was carried out both in solid-liquid and in liquid-liquid two phase systems. The dihalocyclopropane adducts of vinyl phosphates could be obtained in better yield using dihalocarbenes generated by the latter method and no hydrolysis of the vinyl phosphate and of the adduct occurred under these circumstances. Eighteen new vinyl phosphate-dihalocarbene adducts were synthetized and characterized. |
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| Keywords: | 6-amino-2 5-dithiobiureas antimalarial agents thiocarbonyl activated transamination reaction Plasmodium berghei |
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