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Microfluidic separation and capture of analytes for single-molecule spectroscopy
Authors:Kim Samuel  Huang Bo  Zare Richard N
Institution:Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USA.
Abstract:A complex mixture of fluorescently labeled biological molecules is separated electrophoretically on a chip and the constituent molecules are confined in a sub-nanolitre microchamber, which allows analysis by various single-molecule techniques.
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