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A "turn-off" luminescence resonance energy transfer aptamer sensor based on near-infrared upconverting NaYF4:Yb3+,Tm3+ nanoparticles as donors and gold nanorods as acceptors
Authors:Hong-Qi Chen  Juan Xu  Fei Yuan  Yong Wu  Yi-Yan Zhang  Lun Wang
Institution:Anhui Key Laboratory of Chemo-Biosensing, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China
Abstract:Near-infrared upconverting NaYF4:Yb3+, Tm3+ nanophosphors modified with poly(acrylic acid) were prepared and characterized by transmission electron microscopy and luminescence spectroscopy. Based on the observed overlap between the emission spectrum of the NaYF4:Yb3+, Tm3+ nanophosphors and the absorption spectrum of the gold nanorods, we believe that a new “turn-off” luminescence resonance energy transfer aptamer sensor was constructed for sensing thrombin in near-infrared region.
Keywords:NaYF4∶Yb3+  Tm3+ nanophosphors  Gold nanorods  Thrombin  Near-infrared
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