A "turn-off" luminescence resonance energy transfer aptamer sensor based on near-infrared upconverting NaYF4:Yb3+,Tm3+ nanoparticles as donors and gold nanorods as acceptors |
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Authors: | Hong-Qi Chen Juan Xu Fei Yuan Yong Wu Yi-Yan Zhang Lun Wang |
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Institution: | Anhui Key Laboratory of Chemo-Biosensing, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China |
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Abstract: | Near-infrared upconverting NaYF4:Yb3+, Tm3+ nanophosphors modified with poly(acrylic acid) were prepared and characterized by transmission electron microscopy and luminescence spectroscopy. Based on the observed overlap between the emission spectrum of the NaYF4:Yb3+, Tm3+ nanophosphors and the absorption spectrum of the gold nanorods, we believe that a new “turn-off” luminescence resonance energy transfer aptamer sensor was constructed for sensing thrombin in near-infrared region. |
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Keywords: | NaYF4∶Yb3+ Tm3+ nanophosphors Gold nanorods Thrombin Near-infrared |
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