Thermal decomposition of basic aluminium potassium sulfate. Part III. General regularities of thermal dissociation

Using the method of Bolles and Drago (1) the thermodynamic properties of drug - aromatic amino acid complexes were determined calorimetrically. The comparison of K_c evaluated from vapour pressure osmometry. ORD, partition and calorimetry shows a considerable agreement, whereas the data calculated from solubility measurements differ widely from our results. Qualitatively the relationship between solubilisation through different salts and ΔG⁰ for the complexation with the same salts could be demonstrated. Methylxanthines form complexes with anions and cations, the complex formation in H₂O and D₂O, determined calorimetrically, shows the greater stability of the complexes in D₂O.