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The reactions of phenolic reagents with α-bromo Michael acceptors in the K2CO3-acetone system. A stereospecific AdSNE process.
Authors:Vittorio Rosnati  Antonio Saba  Aldo Salimbeni
Affiliation:Istituto di Chimica Organica Via Muroni 25, 07100 Sassari, Italia;Istituto Lusofarmaco d''Italia, Via Carnia 20, 20132 Milano, Italia
Abstract:α-bromo Michael acceptors undergo ipso-substitution by phenol or benzenethiol in the K2CO3-acetone system, the reaction originating the (Z) isomers, via a stereospecific AdSNE process.
Keywords:
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