Highly enantioselective water-compatible organocatalyst for Michael reaction of ketones to nitroolefins |
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| Authors: | Vishnumaya Singh Vinod K |
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| Affiliation: | Department of Chemistry, Indian Institute of Technology, Kanpur, India-208 016. |
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| Abstract: | A chiral diamine was found to catalyze enantioselective addition of ketones to nitroolefins in aqueous/saline/organic media. The products were obtained with excellent diastereoselectivities (syn/anti = 99:1) and enantioselectivities up to 99%. The reaction could be facilitated using a mild acid. [reaction: see text] |
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