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Intestinal absorption of tellurium studied with stable tracers
Authors:M C Cantone  D De Bartolo  G Gambarini  A Giussani  N Molho  L Pirola  Ch Hansen  E Werner  P Roth
Institution:(1) Dipartimento di Fisica dell'Università di Milano, and I.N.F.N. Sezione di Milano, Milano, (Italy);(2) Dipartimento di Fisica del Politecnico di Milano, and I.N.F.N. Sezione di Milano, Milano, (Italy);(3) Institut für Biophysik, Frankfurt/Main, (Germany)
Abstract:An investigation on tellurium metabolism by administration of stable tellurium isotopes124Te and126Te has been performed. Fractional intestinal absorption was determined in rabbits by the double tracer technique. The investigated subjects were given an enriched solution of one tellurium isotope orally and a few minutes later an enriched solution of the other isotope intravenously. The124Te and126Te contents in plasma samples were determined by proton nuclear activation. The methodology described offers a means to study tellurium metabolism in humans without radiation risk.
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