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Simultaneous Determination of Heroin, Amphetamine and their Basic Impurities and Adulterants Using Microemulsion Electrokinetic Chromatography
作者姓名:Tao  WEN  Xia  ZHAO  Guo  An  LUO  Jian  WANG  Yi  Ming  WANG  Pan  LI  Jun  ZHU  Zhong  Shang  YU
作者单位:[1]Department of Chemistry, Tsinghua University, Beijing 100084 [2]Forensic Medical Examination Center of Beijing Public Security Bureau, Beijing 100085 [3]Department of Science & Technology, Public Security Ministry, Beijing 100741 [4]Institute of Forensic Science, Ministry of Public Security P.R.C., Beijing 100038
基金项目:This work was supported by National "10.5" Project (No. 2001DA801B04) and National "863" Project (No. 2002AA2Z2004).
摘    要:Heroin and amphetamine are two most abused drugs that can be highly complex, containing various impurities, byproducts, adulterants and diluents due to differences in the agricultural and manufacturing procedures. Therefore, the comprehensive analysis of above illicit drugs seized or purchased undercover by law enforcement authorities is important for legal and intelligence gathering purposes, and clinical and pharmaceutical purposes as well1. In last decade, micellar electrokinetic chromatogr…

关 键 词:海洛因  分离工艺  安非他明  混杂物  动电学  MEEKC
收稿时间:2005-01-28

Simultaneous Determination of Heroin, Amphetamine and their Basic Impurities and Adulterants Using Microemulsion Electrokinetic Chromatography
Tao WEN Xia ZHAO Guo An LUO Jian WANG Yi Ming WANG Pan LI Jun ZHU Zhong Shang YU.Simultaneous Determination of Heroin, Amphetamine and their Basic Impurities and Adulterants Using Microemulsion Electrokinetic Chromatography[J].Chinese Chemical Letters,2005,16(11):1499-1502.
Authors:Tao;WEN;Xia;ZHAO;Guo;An;LUO;Jian;WANG;Yi;Ming;WANG;Pan;LI;Jun;ZHU;Zhong;Shang;YU
Abstract:Simultaneous separation of 17 species of heroin, amphetamine and their basic impurities and adulterants was conducted within 10 minutes by using capillary microemulsion electrokinetic chromatography. The influences of pH and 1-butanol cosurfactant on the separation were investigated, and 1-butanol was found to be a principal factor to improve separation efficiency.
Keywords:Heroin  amphetamine  microemulsion electrokinetic chromatography  determination  
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