Nucleophilic deoxyfluorination of catechols |
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| Authors: | Nemoto Hiroyuki Nishiyama Tsuyoshi Akai Shuji |
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| Institution: | School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka, Japan. |
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| Abstract: | Nucleophilic deoxyfluorinaiton of one of the two hydroxyl groups of catechols has been developed via the Umpolung concept. This method was successively applied to naturally occurring catechols, such as catechins and dopamine, to produce novel fluorinated analogues. |
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