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Pterocaryquinone, a Novel Naphthoquinone Derivative from Pterocarya tonkinesis
引用本文:刘红兵 蔡兵 崔承彬 颐谦群 赵庆春 管华诗. Pterocaryquinone, a Novel Naphthoquinone Derivative from Pterocarya tonkinesis[J]. 中国化学, 2006, 24(12): 1683-1686. DOI: 10.1002/cjoc.200690315
作者姓名:刘红兵 蔡兵 崔承彬 颐谦群 赵庆春 管华诗
作者单位:[1]Key Laboratory of Marine Drugs, MEC, Marine Drug and Food Institute, Ocean University of China, Qingdao, Shandong 266003, China [2]Beijing Institute of Biomedicine, Beijing 100091, China [3]Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China
摘    要:Pterocaryquinone,a novel 1,4-naphthoquinone derivative,was isolated from Pterocarya tonkinesis and itsstructure was elucidated by spectroscopic methods.Pterocaryquinone is a new dimeric 1,4-naphthoquinone deriva-tive having a pentacyclic skeleton with two five-membered carbon rings,which provided a novel structural skeletonfor 1,4-naphthoquinone derivatives and showed apoptosis-inducing activity toward mouse cancer tsFT210 cells.

关 键 词:东京枫杨 提取 药物 萘醌 苯醌 化学结构 细胞凋亡
收稿时间:2006-03-21
修稿时间:2006-03-212006-05-12

Pterocaryquinone, a Novel Naphthoquinone Derivative from Pterocarya tonkinesis
LIU Hong-Bing,CAI Bing,CUl Cheng-Bin,GU Qian-Qun,ZHAO Qing-Chun,GUAN, Hua-Shi. Pterocaryquinone, a Novel Naphthoquinone Derivative from Pterocarya tonkinesis[J]. Chinese Journal of Chemistry, 2006, 24(12): 1683-1686. DOI: 10.1002/cjoc.200690315
Authors:LIU Hong-Bing  CAI Bing  CUl Cheng-Bin  GU Qian-Qun  ZHAO Qing-Chun  GUAN   Hua-Shi
Affiliation:1. Key Laboratory of Marine Drugs, MEC, Marine Drug and Food Institute, Ocean University of China, Qingdao, Shandong 266003, China;2. Beijing Institute of Biomedicine, Beijing 100091, China ; 3. Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China
Abstract:Pterocaryquinone, a novel 1,4-naphthoquinone derivative, was isolated from Pterocarya tonkinesis and its structure was elucidated by spectroscopic methods. Pterocaryquinone is a new dimeric 1,4-naphthoquinone derivative having a pentacyclic skeleton with two five-membered carbon rings, which provided a novel structural skeleton for 1,4-naphthoquinone derivatives and showed apoptosis-inducing activity toward mouse cancer tsFT210 cells.
Keywords:Pterocarya tonkinesis   naphthoquinone   pterocaryquinone   chemical structure   apoptosis
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