Intramolecular Lewis-acid promoted (2+2) cycloadditions: An efficient total synthesis of (±)-coronafacic acid via an internal Diels-Alder reaction. |
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Authors: | Michael E. Jung Kim M. Halweg |
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Affiliation: | Department of Chemistry, University of California Los Angeles, California 90024 U.S.A. |
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Abstract: | Internal (2+2) cycloaddition of the ester gave the cyclobutene in fair yield; cyclization of the readily derived trienone and hydrolysis produced coronafacic acid in 7% overall yield. |
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