Proposal, verification and comparison of three computer image analysis methods for detection and evaluation of colour glaucomatous changes within the optic disc of a human eye retina |
| |
Authors: | Franti&scaron ek Pluhá ?ek,Jaroslav Pospí &scaron il |
| |
Affiliation: | a Department of Optics of Palacký University, 17. Listopadu 50, 77200 Olomouc, Czech Republic b Department of Experimental Physics and Joint Laboratory of Optics of Palacký University and Institute of Physics of Academy of Sciences, 17. Listopadu 50a, 77200 Olomouc, Czech Republic |
| |
Abstract: | The typical symptom of the human eye glaucoma is a rise and a progression of the bright area (named pallor area) within the retina blind spot. The image analysis manner proposed by the authors detects and suitably numerically describes the relative size of the representative pallor area in the colour digital image of the retina obtained by a suitable fundus camera connected with the computer. Three new different computer image analysis statistical methods for experimental diagnostic evaluation of the obtained characteristic data are proposed in this article: the quantile curves method, the neural net method and the probability density curves method. The quantile curves method is based on the graphical comparison of a relative representative pallor area size with its determined normal value. The neural net and probability density curves methods can automatically and objectively classify the investigated eyes in exactly defined glaucoma risk classes and diagnosed glaucoma with the rated probabilities of incorrect diagnosis determination. All mentioned methods are verified and mutually compared by their application to the large statistical sets of human retina images of various healthy and glaucomatous subjects. |
| |
Keywords: | Glaucoma Optic disc Image analysis Statistical evaluation Neural net |
本文献已被 ScienceDirect 等数据库收录! |