Synthesis of new thieno and pyrazolo[2,1]benzothiazepine derivatives with potential antidepressant properties |
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Authors: | S. Vega,J. A. Dí az,V. Darias,C. C. S Nchez Mateo |
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Affiliation: | S. Vega,J. A. Díaz,V. Darias,C. C. SÁNchez Mateo |
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Abstract: | In this paper we describe a series of new thieno and pyrazolo[2,1]benzothiazepine derivatives 7a‐o which were synthesized by two different methods both starting from the previously described tricyclic alcohols 1–3 . Several components of this series were effective p. o. (per os, orally) in different pharmacological tests currently employed in the evaluation of antidepressant activity. |
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