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Porphyrin derivatives: Synthesis and potential applications
Authors:Jos A S Cavaleiro  Maria G P M Neves  Augusto C Tom  Artur M S Silva  Maria A F Faustino  Paula S Lacerda  Ana M G Silva
Institution:José A. S. Cavaleiro,Maria G. P. M. Neves,Augusto C. Tomé,Artur M. S. Silva,Maria A. F. Faustino,Paula S. Lacerda,Ana M. G. Silva
Abstract:Porphyrin‐porphyrin and porphyrin‐chlorin dimers have been synthesized and evaluated for their photo‐physical and in vivo photodynamic therapy properties. Two of them can become potential new photosensitizers. Study of the reactivity of meso‐tetraaryl porphyrins, as dienophiles, in Diels‐Alder transformations and as dipolarophiles in 1,3‐dipolar cycloadditions, has been undertaken. New synthetic methodologies for certain chlorin, bacteriochlorin and isobacteriochlorin type macrocycles, with potential biological significance, have been established.
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