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A Novel Synthesis of 3-O-Allyl-4, 5, 6-tri-O-benzyl-1-O-(p-methoxybenzyl)-D-myo-inositol
引用本文:ZhiZhouYUE YuanChaoLI. A Novel Synthesis of 3-O-Allyl-4, 5, 6-tri-O-benzyl-1-O-(p-methoxybenzyl)-D-myo-inositol[J]. 中国化学快报, 2005, 16(2): 171-174
作者姓名:ZhiZhouYUE YuanChaoLI
作者单位:ShanghaiInstituteofMateriaMedica,ShanghaiInstitutesforBiologicalSciences,ChineseAcademyofSciences,ZhangjiangHi-TechPark,Shanghai201203
摘    要:Highly efficient synthesis of the entitled compound was achieved from a readily available myo-inositol derivative. The key step involved a desymmetrization with ( )-camphor dimethyl ketal to give two diastereomers. The two diastereomers could be used to synthesize the same compound by changing the orders to introduce the protective groups.

关 键 词:合成方法 3-O-烯丙基-4  5  6-三-O-苯甲基-1-O-(P-甲氧基苯)-D-肌-纤维醇 肌糖 新陈代谢 细胞

A Novel Synthesis of 3-O-Allyl-4, 5, 6-tri-O-benzyl-1-O-(p-methoxybenzyl)-D-myo-inositol
Zhi Zhou YUE,Yuan Chao LI. A Novel Synthesis of 3-O-Allyl-4, 5, 6-tri-O-benzyl-1-O-(p-methoxybenzyl)-D-myo-inositol[J]. Chinese Chemical Letters, 2005, 16(2): 171-174
Authors:Zhi Zhou YUE  Yuan Chao LI
Affiliation:Zhi Zhou YUE,Yuan Chao LI* Shanghai Institute of Materia Medica,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Zhangjiang Hi-Tech Park,Shanghai 201203
Abstract:Highly efficient synthesis of the entitled compound was achieved from a readily availablemyo-inositol derivative. The key step involved a desymmetrization with (+)-camphor dimethylketal to give two diastereomers. The two diastereomers could be used to synthesize the samecompound by changing the orders to introduce the protective groups.
Keywords:nositol   (+)-camphor dimethyl ketal   desymmetrization.
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