Noninvasive determination of tissue optical properties based on radiative transfer theory |
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Authors: | Fujun Zhang Bingquan Chen Shengzhi Zhao Shangming Yang Ruiping Chen Dongcao Song |
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Institution: | a School of Information Science and Engineering, Shandong University, Jinan, Shandong 250100, China;b Institute of Biomedical Optics, Yantai University, Yantai, Shandong 264005, China;c Department of Physics and Engineering Physics, Stevens Institute of Technology, Hoboken, NJ 07030, USA |
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Abstract: | We present a feasibility study of a new method for determining the tissue optical properties, including the absorption and scattering coefficients and the scattering asymmetry factor. A state-of-the-art radiative transfer model for the coupled air/tissue system, based on rigorous radiative transfer theory, is used in our forward modeling simulations. The concept of the effective photon penetration depth is introduced and used to help determine the depth below, which information about the tissue will not be available through noninvasive imaging of a biological tissue using reflected diffuse light. Simulation results show that for accurate determination of tissue optical properties, one can use radiative transfer theory in conjunction with measurements of reflected radiances as well as other existing techniques. |
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Keywords: | Author Keywords: Tissue optical properties Radiative transfer Reflected radiances |
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