| 水溶性亚胺配体/钯催化的室温 Suzuki 反应 |
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| 引用本文： | 刘春,倪祁健,胡萍萍,袁浩,金子林. 水溶性亚胺配体/钯催化的室温 Suzuki 反应[J]. 催化学报, 2010, 31(10): 1277-1280. DOI: 10.3724/SP.J.1088.2010.00412 |
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| 作者姓名： | 刘春 倪祁健 胡萍萍 袁浩 金子林 |
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| 作者单位： | 大连理工大学化工学院精细化工国家重点实验室,辽宁大连,116012 |
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| 基金项目： | 国家自然科学基金，教育部长江学者和创新团队发展计划，精细化工国家重点实验室开放课题，大连理工大学理学研究基金及研究生教育改革基金 |
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| 摘 要： | 设计并合成了一种新型水溶性亚胺双齿配体 I, 并得到其单晶结构. 该配体具有半配位效应和绿色化学特征, 与氯化钯组成的催化体系在空气和室温条件下, 可有效催化乙醇水溶液中的溴代芳烃与芳基硼酸的 Suzuki 交叉偶联反应. 在 n(ArBr) = 0.5 mmol, n(ArB(OH)2) = 0.75 mmol, x(PdCl2) = 1%, x(I) = 2%, n(K2CO3) = 1.0 mmol, c(EtOH) = 50% 水溶液的优化条件下, 经 20 min 反应, 分离收率即可达到 99%.
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| 关 键 词： | Suzuki 反应 交叉偶联 亚胺配体 钯 水相 |
| 收稿时间： | 2010-10-25 |
Water-Soluble Imine Ligand/Palladium-Catalyzed Suzuki Reaction at Room Temperature |
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| LIU Chun,NI Qijian,HU Pingping,YUAN Hao,JIN Zilin. Water-Soluble Imine Ligand/Palladium-Catalyzed Suzuki Reaction at Room Temperature[J]. Chinese Journal of Catalysis, 2010, 31(10): 1277-1280. DOI: 10.3724/SP.J.1088.2010.00412 |
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| Authors: | LIU Chun NI Qijian HU Pingping YUAN Hao JIN Zilin |
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| Affiliation: | State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian 116012, Liaoning, China |
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| Abstract: | A new air-stable and water-soluble imine ligand (I) has been synthesized and its single crystal structure has been characterized. This N,O-bidentate ligand, with the possible hemilability and the property of green chemistry, is efficient in the palladium-catalyzed Suzuki cross-coupling of aryl bromide and aryl-boronic acid at room temperature in aqueous ethanol. Under the optimized reaction conditions (i.e., n(ArBr) = 0.5 mmol, n(ArB(OH)2) = 0.75 mmol, x(PdCl2) = 1%, x(I) = 2 mol%, n(K2CO3) = 1.0 mmol, and c(EtOH) = 50% aqueous solu-tion), a 99% isolated yield of the product was obtained in 20 min. |
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| Keywords: | Suzuki reaction cross-coupling imine ligand palladium aqueous media |
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