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Si-rhodamine based water-soluble fluorescent probe for bioimaging of Cu+ |
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| Authors: | Xiaoyun Chai Weiwei Zhu Qingguo Meng Ting Wang |
| Institution: | Department of Organic Chemistry, College of Pharmacy, Second Military Medical University, Shanghai 200433, China; College of Pharmacy, Yantai University, Yantai 264005, China |
| Abstract: | A Si-substituted rhodamine based water-soluble fluorescent probe bearing a tetrathia-azacrown was designed for fluorescence imaging of Cu+ with substantial affinity and selectivity. In physiological condition, the developed probe with outstanding water-solubility exhibits ultrahigh sensitivity to Cu+, ensuring the reliable fluorescence imaging in vivo. |
| Keywords: | Si-rhodamine Near-infrared Water-solubility Fluorescence imaging Copper |
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