| 基于飞行时间技术的PET发展历史与现状 |
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| 引用本文： | 贠明凯,李婷,章志明,张玉包,单保慈,魏龙. 基于飞行时间技术的PET发展历史与现状[J]. 原子核物理评论, 2012, 29(2): 162-168. DOI: 10.11804/NuclPhysRev.29.02.162 |
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| 作者姓名： | 贠明凯 李婷 章志明 张玉包 单保慈 魏龙 |
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| 作者单位： | 1.中国科学院高能物理研究所, 北京 100049;2.中国科学院核分析技术重点实验室, 北京 100049;3.北京市射线成像技术与装备工程技术研究中心, 北京 100049 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 简要介绍了基于飞行时间（Time of Flight， 简称TOF）技术的正电子发射断层扫描成像（Positron Emission Tomography， 简称PET）的基本原理， 回顾了TOF-PET成像设备的发展历史， 讨论了影响TOF PET时间分辨率的主要因素， 并对TOF-PET给图像重建技术带来的挑战进行了分析。 最后， 重点介绍了TOF-PET技术所带来的优势， 使用TOF技术可以有效地改善图像质量， 并且为临床诊断和临床前研究带来便利。 The principle of time of flight (TOF) positron emission tomography (PET) and a brief review of the history of TOF-PET are introduced. The factors influencing the time resolution of a TOF-PET scanner are presented， especially focus on the intrinsic properties of scintillators and front end electronics. Challenges and achievements of the structure of data organization and image reconstruction are reviewed. Finally， the benefits of TOF-PET on image quality improvement and tumor detection are emphasized.
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| 关 键 词： | PET TOF TOF图像重建 图像质量 |
| 收稿时间： | 1900-01-01 |
History and Current Status of PET Devolopment based on Time of Flight |
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| YUN Ming-kai,LI Ting,ZHANG Zhi-ming,ZHANG Yu-bao,SHAN Bao-ci,WEI Long. History and Current Status of PET Devolopment based on Time of Flight[J]. Nuclear Physics Review, 2012, 29(2): 162-168. DOI: 10.11804/NuclPhysRev.29.02.162 |
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| Authors: | YUN Ming-kai LI Ting ZHANG Zhi-ming ZHANG Yu-bao SHAN Bao-ci WEI Long |
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| Affiliation: | 1.Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China;2.Key Laboratory of Nuclear Analytical Techniques, Chinese Academy of Sciences, Beijing 100049, China;3.Beijing Engineering Research Center of Radiographic Techniques and Equipments, Beijing 100049, China |
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| Abstract: | The principle of time of flight(TOF) positron emission tomography(PET) and a brief review of the history of TOF-PET are introduced.The factors influencing the time resolution of a TOF-PET scanner are presented,especially focus on the intrinsic properties of scintillators and front-end electronics.Challenges and achievements of the structure of data organization and image reconstruction are reviewed.Finally,the benefits of TOF-PET on image quality improvement and tumor detection are emphasized. |
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| Keywords: | PET TOF TOF imaging reconstruction image quality |
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