A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L.

A new alkylene dihydrofuran glycoside (1) was isolated from the root bark of Morus alba L., along with moracin M-3′-O-β-D-glucopyranoside (2), and moracin M-6, 3′-di-O-β-D-glucopyranoside (3). Compound 1 was identified as 2-methylene-3-methoxy-2, 5-dihydrofuran-4-O-β-D-glucopyranoside on the basis of chemical and spectroscopic data including 1D and 2D NMR spectral analysis. In addition, the antioxidant activity of 1 was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay. The IC50 values were 2.49 and 0.45 mg/mL, respectively.