Polyfluoroalkoxy phosphonic and phosphinic acid derivatives: II. Reversible esterase inhibitors |
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| Authors: | V V Krutikova V I Krutikov A V Erkin |
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| Institution: | 1.St. Petersburg State Institute of Technology,St. Petersburg,Russia |
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| Abstract: | Polyfluoroalkyl esters of phosphoric, alkylphosphonic and 1-hydroxypolyfluoroalkylphosphonic acids exhibited significant antiesterase activity against various esterases of animal and microbial origin. Moreover, with some compounds reversible inhibition of enzymes was observed due to the specific influence of hydrophobic fragments of the target products. |
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