fMRI pain activation in the periaqueductal gray in healthy volunteers during the cold pressor test |
| |
| Authors: | S. La Cesa E. Tinelli N. Toschi G. Di Stefano S. Collorone A. Aceti A. Francia G. Cruccu A. Truini F. Caramia |
| |
| Affiliation: | 1. Department of Neurology and Psychiatry, University Sapienza, Rome, Italy;2. Medical Physics Section, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy;3. Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Boston, MA 02219, USA;4. Harvard Medical School, Boston, MA 02115, USA |
| |
| Abstract: | The periaqueductal gray (PAG), a brain area belonging to the descending pain modulatory system, plays a crucial role in pain perception. Little information is available on the relationship between PAG activation and perceived pain intensity. In this study, we acquired functional magnetic resonance imaging (fMRI) scans from the PAG during the cold pressor test, a model for tonic pain, in 12 healthy volunteers. fMRI data were acquired with a 12-channel head-coil and a 3-Tesla scanner and analyzed with Statistical Parametric Mapping (SPM8) software. |
| |
| Keywords: | Descending modulatory system Fibromyalgia Periacqueductal gray fMRI Cold pressor test |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
