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Measuring steady-state cerebral vasomotor reactivity using non-triggered phase-contrast magnetic resonance imaging |
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| Authors: | Chun-Jung Juan Yi-Jui Liu Teng-Yi Huang Cheng-Yu Chen Guo-Shu Huang |
| Institution: | 1. Department of Radiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, ROC;2. Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, ROC;3. Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, ROC;4. Graduate Institute of Clinical Medcine, Taipei Medical University, Taipei, Taiwan, ROC |
| Abstract: | To investigate cVMR by using CO2-based hypercapnic challenge and blood flow monitoring employing non-triggered phase contrast (PC) magnetic resonance imaging. Six healthy volunteers (6 male; mean age: 29 years) participated this study after providing institutionally approved consent. This study used non-triggered PC imaging to increase temporal resolution of dynamic blood flow measurements, allowing real-time monitoring of the hypercapnic challenge response. Results suggest that vasomotor reactivity measured by non-triggered PC imaging is positively associated with the concentration of inhaled CO2. This study concludes that CO2 challenge combined with non-triggered PC flow imaging is potentially useful to provide diagnostic information for patients with cerebrovascular disease. |
| Keywords: | Cerebral vasomotor reactivity MR phase contrast Blood flow |
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