Yojironins A−D, meroterpenoids and prenylated acylphloroglucinols from Hypericum yojiroanum |
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Authors: | Takuji MamemuraNaonobu Tanaka Azusa ShibazakiTohru Gonoi Jun’ichi Kobayashi |
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Institution: | a Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan b Medicinal Mycology Research Center, Chiba University, Chiba 260-0856, Japan |
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Abstract: | Two new meroterpenoids, yojironins A (1) and B (2), were isolated from the whole plants of Hypericum yojiroanum, together with two new prenylated acylphloroglucinols, yojironins C (3) and D (4). Their structures were elucidated by spectroscopic data. Yojironins A (1) and B (2) are biogenetically unique meroterpenoids, which seem to be composed of two acetate units with a 2-methylbutanoyl group and three isoprene units. Yojironin A (1) exhibited antimicrobial activity. |
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Keywords: | Hypericum yojiroanum Meroterpenoids Prenylated acylphloroglucinols Yojironins A&minus D |
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