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Yojironins A−D, meroterpenoids and prenylated acylphloroglucinols from Hypericum yojiroanum
Authors:Takuji MamemuraNaonobu Tanaka  Azusa ShibazakiTohru Gonoi  Jun’ichi Kobayashi
Institution:a Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
b Medicinal Mycology Research Center, Chiba University, Chiba 260-0856, Japan
Abstract:Two new meroterpenoids, yojironins A (1) and B (2), were isolated from the whole plants of Hypericum yojiroanum, together with two new prenylated acylphloroglucinols, yojironins C (3) and D (4). Their structures were elucidated by spectroscopic data. Yojironins A (1) and B (2) are biogenetically unique meroterpenoids, which seem to be composed of two acetate units with a 2-methylbutanoyl group and three isoprene units. Yojironin A (1) exhibited antimicrobial activity.
Keywords:Hypericum yojiroanum  Meroterpenoids  Prenylated acylphloroglucinols  Yojironins A&minus  D
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