Non-covalent interactions of a drug molecule encapsulated in a hybrid silica gel |
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| Authors: | Paul Geo Steuernagel Stefan Koller Hubert |
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| Affiliation: | Institut für Physikalische Chemie and Graduate School of Chemistry, Westf?lische Wilhelms-Universit?t, Corrensstrasse 36, Münster, Germany. |
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| Abstract: | The drug molecule Propranolol has been encapsulated by a sol-gel process in an organic-inorganic hybrid matrix by in-situ self-assembly; the 2D HETCOR solid state NMR spectroscopy provides direct proof of the intimate spatial relationship between the host matrix and guest drug molecules. |
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