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Phytochemical Study on Some Polyphenols of <Emphasis Type="Italic">Geranium pyrenaicum</Emphasis>
Authors:C S Fodorea  L Vlase  S E Leucuta  M Tamas
Institution:(1) Faculty of Dental Medicine and Pharmacy, University “Ovidius”, Constanta, Romania;(2) Faculty of Pharmacy, University of Medicine and Pharmacy “Iuliu Hatieganu”, Cluj-Napoca, Romania
Abstract:In order to continue our previous studies concerning Geranium pyrenaicum Burm. (Geraniaceae), we have performed spectrophotometric determinations and a HPLC study of some polyphenols. We have analyzed the dried Geranii pyrenaici herba (harvested from Cluj-Napoca, district of Cluj, Romania). We have established the content in flavonoids (0.316%), phenolic acids (0.099%), tannins (5.295%), and anthocyanins (12.030 mg/100 g vegetal product). We have identified and measured by HPLC the following compounds: hyperoside (21.61 μg/100 mg), ellagic acid (1810.44 μg/100 mg), isoquercitrine (11.197 μg/100 mg), and caftaric acid (76.83 μg/100 mg). We have also analyzed by HPLC a hydrolyzed sample of the same drug in which we have identified and measured: ellagic acid (4139.33 μg/100 mg), quercetol (29.65 μg/100 mg), kaempherol (41.48 μg/100 mg), and caftaric acid (20.721 μg/100 mg). __________ Published in Khimiya Prirodnykh Soedinenii, No. 4, pp. 322–324, July–August, 2005.
Keywords:Geranium pyrenaicum Burm    polyphenol  HPLC  spectrophotometric methods
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