Microwave-assisted solid-phase synthesis of phthalimides |
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Authors: | Martin Bénédicte Sekljic Harald Chassaing Christophe |
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Affiliation: | Intervet Innovation GmbH, zur Propstei, Drug Discovery, Lead Optimization D-55270, Schwabenheim, Germany. |
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Abstract: | [reaction: see text] A traceless solid-phase synthesis of substituted phthalimides is proposed. The target compounds are obtained within minutes by a microwave-assisted cyclative cleavage in good yields and excellent purities. |
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