Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine |
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| Authors: | Krishnan Sadagopan Hvastkovs Eli G Bajrami Besnik Jansson Ingela Schenkman John B Rusling James F |
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| Affiliation: | Department of Chemistry (U-60), 55 N. Eagleville Rd., University of Connecticut, Connecticut, USA. |
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| Abstract: | We report for the first time voltammetric/electrochemiluminescent sensors applied to predict genotoxicity of N-nitroso compounds bioactivated by human cytochrome P450 enzymes. |
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