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Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine
Authors:Krishnan Sadagopan  Hvastkovs Eli G  Bajrami Besnik  Jansson Ingela  Schenkman John B  Rusling James F
Institution:Department of Chemistry (U-60), 55 N. Eagleville Rd., University of Connecticut, Connecticut, USA.
Abstract:We report for the first time voltammetric/electrochemiluminescent sensors applied to predict genotoxicity of N-nitroso compounds bioactivated by human cytochrome P450 enzymes.
Keywords:
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