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Capillary GC-MS investigation of the metabolism and excretion of oxabolone in man
Authors:Maria Vittoria Barbarulo  Francesca Buiarelli  Massino Ciardi  Alberto Giarrusso  Felice Rosati  G. P. Cartoni
Abstract:The metabolism of oxabolone cipionate, 17-(3-cyclopentyl-1-oxopropoxy)-4-hydroxyestr-4-en-3-one, a synthetic anabolic steroid, was investigated in man, the cumulative urinary excretion and the metabolism of the compounds being studied by GC-MS in both electron impact and chemical ionization modes. After administration by injection to volunteers, five different metabolities were detected in urine. The metabolites and the parent compound were detected in urine up to a week after administration.
Keywords:Capillary GC-MS  Metabolism  Oxabolone
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