Synthesis of 2,5 -Bis(4-methyl-2-thienyl)thiophene and 2,5-Bis(4-methyl-2-thienyl)pyrrole |
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Authors: | Thung-Mei H. Luo Liang-Huei Chen |
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Abstract: | Syntheses of 2,5-bis(4-methyl-2-thienyl)thiophene 3 and 2,5-bis(4-methyl-2-thienyl)pyrrole 4 are described. The key step involves Stetter reaction between 4-methyl-2-thiophenecarboxaldehyde and divinyl sulfone. Cyclizaton of the resulting 1,4-bis-(4-methyl-2-thienyl)-1,4-butanedione 2 with Lawesson's reagent gives 2,5-bis(4-methyl-2-thienyl)thiophene 3, whereas condensation with ammonium acetate provides the 2,5-bis(4-methyl-2-thienyl)pyrrole 4. |
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Keywords: | 1,4-Bis-(4-methyl-2-thienyl)-1,4-butanedione 2,5-Bis(4-methyl-2-thienyl)thiophene 2,5-Bis(4-methyl-2-thienyl)pyrrole |
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